Endocrine Abstracts

Synthesis of thyroid hormones by the fetal thyroid requires the passage of iodide through the placenta. In the thyroid active iodide transport is facilitated by three transporters, the sodium iodide symporter (NIS), Pendrin (PDS) and the recently described the human apical iodide transporter (hAIT). Simultaneous expression of all three transporters appears to be thyroid restricted and although extrathyroidal expression of individual transporters has been reported, relatively l...